NG Biotech CARBA-5

For rapid detection of Carbapenemases
Improved range of variants now detected across all ‘big 5’ carbapenemase families for infection prevention and control purposes.

The NG Biotech CARBA 5 detects multiple mechanisms, giving a clearer picture of the problem as a whole, aiding treatment decisions and helping to inform isolation/PPE decisions etc. whilst also assisting in infection control and supporting #antimicrobialstewardship.

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Overview

NG-Test CARBA 5 aids in the rapid identification of carbapenemase-producing Enterobacterales and Pseudomonas aeruginosa in healthcare settings.

NG-Test CARBA-5 detects one or more of the five common types of carbapenemase enzymes (KPC (K), OXA-48-like (O), IMP (I), VIM (V), NDM (N)) from carbapenem-non-susceptible Gram-negative bacterial colonies.

PHE Report: Commercial assays for the detection of acquired carbapenemases

Detection of KPC, NDM and VIM-Producing Organisms Directly from Rectal Swabs by a Multiplex Lateral Flow Immunoassay (2021)

Evaluation of NG-Test Carba 5 for Rapid Phenotypic Detection and Differentiation of Five Common Carbapenemase Families: Results of a Multicenter Clinical Evaluation (2020)

Improvement of the Immunochromatographic NG-Test Carba 5 Assay for the Detection of IMP Variants Previously Undetected (2019)

NG-Test Carba 5 for Rapid Detection of Carbapenemase-Producing Enterobacterales from Positive Blood Cultures (2019)

Evaluation of the NG-Test CARBA 5 multiplex immunochromatographic assay for the detection of KPC, OXA-48-like, NDM, VIM and IMP carbapenemases (2018)

A multiplex lateral flow immunoassay for the rapid identification of NDM-, KPC-, IMP- and VIM-type and OXA-48-like carbapenemase-producing Enterobacteriaceae (2018)