NG Biotech CTX-M MULTI
For rapid detection of Extented Spectrum Beta-Lactamase (ESBL)
The CTX-M family of extended spectrum beta-lactamases (ESBL) are frequently found in both healthcare and community settings and are the most common class of ESBL
The production of beta-lactamases, enzymes that degrade the beta-lactam ring of the beta-lactam family of antibiotics, are a common resistance mechanism found in Gram-negative bacteria, particularly Enterobacterales.
There are different classes of beta-lactamase, each of which has a different spectrum of activity. The CTX-M class of beta-lactamases is important due to the extended spectrum of activity against penicillins and cephalosporins, including third generation cephalosporins. This makes Gram-negative bacteria that carry CTX-M enzymes more difficult to treat, requiring broader spectrum agents, such as piperacillin/tazobactam.
The NG Biotech CTX-M MULTI tests are an important tool that identify one of the important mechanisms of resistance to cephalosporins commonly found in Enterobacterales and inform appropriate prescribing #antimicrobialstewardship.
NG-Test CTX-M multiplex detects variants belonging to all five known CTX-M groups: 1, 2, 8, 9 & 25.